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A job that a person doesn’t like is much more harmful to his psyche than no job at all..

The liver is the heaviest organ in our body.

The rarest disease is Kuru disease. Only members of the For tribe in New Guinea suffer from it. The patient dies of laughter. The disease is believed to be caused by eating human brains. Millions of bacteria are born, live and die in our intestines. They can only be seen under high magnification, but if they were put together, they would fit in a regular coffee cup. The average life expectancy of left-handers is shorter than that of right-handers. Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.

In order to say even the shortest and simplest words, we use 72 muscles. Besides people, only one living creature on planet Earth suffers from prostatitis - dogs. These are truly our most faithful friends. A person taking antidepressants will, in most cases, become depressed again. If a person has coped with depression on his own, he has every chance to forget about this condition forever. Immunity is our natural defense against a wide variety of infectious pathologies. She is able to successfully cope with both viral and bacterial infections.

The development of carcinoid syndrome is caused by a hormonally active tumor arising from enterochromaffin cells (argentaffinny) intestinal cells (Kulchitsky cells). In this case, increasing intestinal disorders are accompanied by hypertensive syndrome (Gogin E.E., 1991). Until 1953, every case of carcinoid syndrome was considered casuistic. However, since the description of the clinical picture of the disease, the frequency of detection of carcinoid tumors has increased significantly. However, intravital diagnosis of carcinoid syndrome is quite rare. According to autopsy materials, carcinoids occur in 0.14–0.15% of cases.

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Most often, carcinoid tumors are localized in the gastrointestinal tract, less often they occur in the bronchi, gall bladder, pancreas and ovaries. The sizes of tumors, as a rule, are not large and vary from 0.1 to 3 cm. The catinoid cell is polygonal, has chromatin and a large number of randomly located granules. The connective tissue stroma of a carcinoid tumor contains a significant number of mast cells, which have the ability to concentrate and possibly produce serotonin.

The pathogenesis of carcinoid syndrome is based on the production of 5-hydroxytryptamine (serotonin, enteramine) by tumor cells, which causes hyperserotoninemia and an excess of other physiologically active substances. The classic symptoms of carcinoid syndrome with a significant increase in blood pressure develop only when the primary focus or metastases of the tumor are outside the hepatic barrier. In these cases, the serotonin produced by tumor cells is not destroyed and enters the general circulation through the hepatic vein, causing various pathological conditions.

The vasoconstrictor effect of serotonin was the first of its properties to become known. Most researchers have found a hypertensive reaction when administering serotonin to humans. However, there is a sufficient number of studies indicating that after giving serotonin there is a decrease in blood pressure. The nature of the vascular reaction in response to serotonin is influenced by the method of its administration. Thus, when administered intravenously, an increase in minute volume and blood pressure is observed, and when serotonin is administered intraperitoneally, a hypotensive reaction is observed. It is believed that the variability in blood pressure responses to serotonin is associated with the ability of the vascular bed to respond differently to this amine.