Numerous studies have been conducted on the use of interferon-О� in patients with carcinoid tumors. To treat patients, doses of О�-interferon 3-9 IU were used subcutaneously 3-7 times a week. The use of higher doses of the drug does not improve treatment rates, but significantly increases the percentage of toxic reactions. When treated with О�-interferon, improvement is observed in 30-75% of cases.
Treatment of arterial hypertension is carried out according to general rules. In some cases, treatment should be aimed at combating complications of carcinoid syndrome, such as cardiovascular failure, gastrointestinal bleeding, etc. It should be noted that the duration of the disease (10 years or more), significant exhaustion of patients with carcinoid syndrome requires the appointment of restorative therapy. What is Carcinoid Syndrome Pathogenesis (what happens?) during Carcinoid Syndrome Symptoms of Carcinoid Syndrome Diagnosis of Carcinoid Syndrome Treatment of Carcinoid Syndrome Which doctors should you contact if you have Carcinoid Syndrome.
Carcinoids are the most common tumors of neuroendocrine cells (cells of the APUD system). These cells are derivatives of the neural crest. They are widely distributed in the body and contain and secrete some biologically active peptides. Most often, carcinoids develop in the gastrointestinal tract (85%), especially in the small intestine, as well as in the lungs (10%), less often affecting other organs (for example, the ovaries). Intestinal carcinoids rarely (in 10% of cases) manifestclinically. This is explained by the rapid destruction of biologically active peptides in the liver.
Only with metastases of intestinal carcinoid to the liver do symptoms appear in 40-45% of patients. As for ovarian and bronchial carcinoids, they are capable of causing a characteristic syndrome in the early stages of the disease. Carcinoid syndrome is a combination of symptoms that arise due to the release of hormones by tumors and their release into the bloodstream.